Urate-Lowering Drugs and Prevention of Cardiovascular Disease
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چکیده
منابع مشابه
Urate-Lowering Drugs and Prevention of Cardiovascular Disease: The Emerging Role of Xanthine Oxidase Inhibition.
The relevance of elevated plasma levels of serum uric acid (SUA) in patients with cardiovascular disease was historically described 2 centuries century ago when Alexander Heig published a paper dealing with the causative role of hyperuricermia in patients with hypertension and several other diseases. More recently, a remarkable number of epidemiological and experimental studies have demonstrate...
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Cardiovascular disease (CVD) is a very common, if not the most common, cause of morbidity and mortality in developed countries, and there has been longstanding recognition that diabetes is a potent risk factor for CVD.1–3 Individuals with either type 1 or type 2 diabetes mellitus manifest CVD rates up to 4 to 10 times higher than those observed in nondiabetic subjects. Subjects with diabetes al...
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BACKGROUND The benefits of blood pressure lowering treatment for prevention of cardiovascular disease are well established. However, the extent to which these effects differ by baseline blood pressure, presence of comorbidities, or drug class is less clear. We therefore performed a systematic review and meta-analysis to clarify these differences. METHOD For this systematic review and meta-ana...
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OBJECTIVE To determine in a Canadian health care setting the cost effectiveness of urate lowering drugs (ULD) in the treatment of nontophaceous gouty arthritis with recurrent attacks and to evaluate the least costly regimen among available ULD. METHODS A decision analysis model was designed using hypothetical cohort of patients who present 1 to 4 recurrent attacks/year. It incorporated costs ...
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Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2016
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.115.06531